nFast- nano technology approach
We are developing a nanotechnology approach to enhance the solubility, bioavailability, and effectiveness of API crystals by improving their water solubility without altering the crystal structure. The technology aims to reformulate various insoluble APIs falling under BCS Class II and IV with bioabsorbable, functionalized nanoparticles to enhance solubility and ultimately efficacy. These fast-dissolving APIs will […]
Visualize, Measure and Track Skin Abnormalities (ViMeT)
Healthcare domain lacks objective data in measuring wounds accuratley and consistently. We developed a system to scan skin abnormalities (which includes wounds), to consistently measure, and to track the measurements. The system is semi-automated, can keep track of the measures by patient and by provider over time, can predict healing, and visualize wounds and measurements […]
A novel cyclic peptide therapeutic platform for the treatment of Multiple Sclerosis, and broader autoimmunity
Multiple sclerosis (MS) is an autoimmune inflammatory disease characterized by cranial and spinal cord demyelination, driven by B-cell- and T-cell-mediated mechanisms. The current MS therapeutic market is dominated by monoclonal antibody therapies, with an emphasis on depleting whole or partial immune B-cell populations. Although recent therapies are partially efficacious, their concurrent and broad-spectrum effects (both […]
ESSENCE – A multiplexed POC device for the detection of Zoonotic Diseases
Animal diseases pose significant economic, health, and security risks, threatening the $236B U.S. food industry and public health through zoonotic outbreaks. Rapid, field-deployable diagnostic tools are essential for early detection and containment. Dr. Sagnik Basuray’s ESSENCE platform, a modular, microfluidic bio-detection system, enables multiplex detection of animal and zoonotic diseases from a single sample. Currently […]
CidaGel: Injectable Gel for Dental Pulp Regeneration
CidaGel is a novel antimicrobial gel that will be evaluated for preclinical studies in preparation for an FDA 510k submission for use in abrogating infection and enhancing dental pulp tissue ingrowth in teeth. Through the process of this award, we will in: Phase-1 TITA will focus on Research and Proof of Validation in collaboration to […]
Development of a Novel Peptide Tracer for Tracing Potential Septic Pollution Sources
We propose to develop a novel peptide tracer to be used for detecting and quantifying the relative contributions of the septic systems in lake communities to the nutrient loads to the lakes that lead to HAB and help prioritize the community efforts to improve nutrient treatments in those septic systems. We plan to apply this […]
Climate-Smart Electrocatalytic Membrane Technology Transforms Nitrate Pollution into Enhanced Ammonium Salt Fertilizer
Dr. Wen Zhang’s group at NJIT plans to develop novel flow-through electrocatalytic membrane systems to recover nutrients such as nitrate or ammonia (NH3). This cutting-edge electrocatalytic membrane technology has proven effective for NO3b conversion into NH3 with concurrent NH3 recovery as valuable products such as ammonia salt fertilizers.
Rapid, Robust, Cost-effective, Field-based, AI-integrated point-of-use Electrochemical Platform Technology for in-situ detection and quantification of PFAS in source water.
The U.S. PFAS analytical instrumentation market is projected to grow from $75M in 2021 to over $350M by 2028, driven by regulatory actions and increasing contamination awareness. Current lab-based PFAS testing is costly and slow, necessitating a portable, high-sensitivity electrochemical sensor. We propose ESSENCE, an integrated electrochemical sensor platform for rapid, in-situ PFAS detection using […]
High-frequency and High Power Ultrasound and Argon Nanobubbles for Destruction of Emerging Contaminants
To eliminate emerging contaminants such as PFAS, microplastics, pharmaceuticals, and pathogens require robust and energy-saving methods. The synergy of nanobubble technology with ultrasound is emerging as an optimal solution, bolstering the destruction capabilities of ultrasound while simultaneously reducing energy consumption. This approach requires significantly less energy and fewer resources, making it an ideal solution for […]
A Novel Mid-Wave Infrared Light Emitter Development
Commercial NDIR devices commonly rely on incandescent lamp light source and low sensitivity thermal detector, which not only exhibit limited effective emission sensitivity to interact with gas molecules but also possess a low electrical modulation rate due to their inherently slow response times for switching on and off during operation (i.e., <10 Hz). Therefore, this […]
