Novel Assay Platform for Detection of Ubiquitinated Tau as an Alzheimer’s Disease Biomarker
Alzheimer’s disease (AD) is the most prevalent neurodegenerative condition in the United States, imposing a significant economic burden on society. Costs surpassed $345 billion in 2023 and are projected to reach $1 trillion by 2050, as reported by the Alzheimer’s Association. Early and accurate diagnosis of AD and related dementias (ADRD) is crucial for effective […]
Music for Listeners with Autism: An Online Platform for Collecting Music Interaction Data from Children with Autism
This project develops an interactive, web-based music platform tailored for children with Autism Spectrum Disorders (ASD). By allowing users to modify musical elements, it promotes participatory listening and captures data on preferences and engagement. The goal is to enhance enjoyment, social-emotional development, and inform music therapy and composition. The platform has potential applications in education, […]
Engineering Functional Macrophage Immune Cells for Persistent Phenotype and Survival
The proposed work will leverage our expertise in regulating macrophage phenotype with materials-based approaches and devices for production of engineered cell therapies. The device investigated in this work for improved manufacture of these emerging technologies has been previously demonstrated for engineering of for adoptive T-cell therapies (ATCTs) and is built upon a well-established partnership with […]
Modular Wireless Battery System Technology for Electrified Fleet Vehicles
The main objective of the project is to develop a battery system technology for electric fleet vehicles that results in reduced downtime due to charging, reduced range anxiety, elimination for the need for initial investment in larger battery capacity, allows for sharing battery modules easily and safely between fleet vehicles, and allows for the ability […]
Enhancing Climate Resilience in Geosciences at Clemson University
Abstract This project addresses critical gaps in climate resilience planning for low-capacity communities, which often lack access to data, tools and technical expertise needed to mitigate risk. It introduces a scalable solution that builds on Clemson’s prior work by integrating advanced geospatial analysis, community engagement strategies, and collaboration across South Carolina agencies and academic institutions. […]
Developing Scalable Technology and Evaluating Customer Segments for a Novel Mental Health App with a Customizable AI-Driven Virtual Therapeutic Coach
Abstract: This proposal addresses the rising mental health crisis among college students, a population that has experienced a substantial increase in depression rates over the past decade. We propose a novel solution in the form of a customizable mobile mental health (MHealth) app that combines evidence-based therapeutic strategies with an AI-powered virtual therapeutic coach. Backed […]
StressDetect: Real-Time Monitoring CHO Cell Stress to Enhance Biopharmaceutical Production
The primary objective of this project is to validate StressDetect as an innovative real time stress-monitoring tool for CHO cell-based biomanufacturing through the following stages: 1. Develop/Standardize ROS Modulation in CHO Cultures to Simulate Industry Conditions, 2. Validate StressDetect as Industry-Ready Stress Monitoring Tools, 3. Optimize and Pilot-Test StressDetect for Biomanufacturing Commercialization. Finally, collaborate with […]
Revolutionizing Water Level Monitoring with Intelligent River® Technology
Water level monitoring plays a vital role in ensuring public safety, managing natural resources, and sustaining economic activities. The Clemson Intelligent River® platform includes technologies, systems, and methods to monitor water quantity using embedded devices that can stream data in near real-time to customers and stakeholders. This project supports the further development and testing of […]
Digital Twin-Driven UAV Ignition: Revolutionizing Prescribed Fire Planning for Safer, Smarter Wildfire Prevention
This proposal addresses the limitations of current prescribed burn practices, which often fall short of their intended protective outcomes and can even harm forest ecosystems due to poor planning and reliance on outdated methods. It introduces a novel solution that combines UAV-based aerial ignition with a digital twin of the forest environment. This virtual platform […]
Collaborative University Research for Real-world Engagement in New Water Technologies
The vision for our Accelerating Research Translation (ART) program is to create and maintain a thriving, sustainable, and innovative translational research ecosystem. With this supplement opportunity, we will refi ne our ART approach to further develop Translational Research in the geosciences. We will engage faculty, postdocs, and students with water-related interests and expertise across campus […]