STRP

New Jersey Institute of Technology

nFast- nano technology approach

Lead: Som Mitra

Partner: Sai Rang Rao, Marc Long

Keywords: drug development, nano technology, API

Amount: $75000

Intellectual Property Status: Patent

Award Date: 06/30/2024

End Date: 06/30/2025

ABSTRACT

We are developing a nanotechnology approach to enhance the solubility, bioavailability, and effectiveness of API crystals by improving their water solubility without altering the crystal structure. The technology aims to reformulate various insoluble APIs falling under BCS Class II and IV with bioabsorbable, functionalized nanoparticles to enhance solubility and ultimately efficacy. These fast-dissolving APIs will be applicable in oral, transdermal, inhalation, and injectable formulations, lowering the required dosage and thereby reducing side effects and toxicity.

This is not the NSF website for the ART program. The development of this portal is supported by the U.S. National Science Foundation under Award No. 2331429. The material on this portal is sourced from the various activities and projects being supported the ART program. Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the U.S. National Science Foundation.

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