STRP

New Jersey Institute of Technology

Deep Learning and Large Language Models for Personalized Cancer Vaccine Design

Lead: Zhi Wei

Partner: The Center of Applied Genomics (CAG), the Children’s Hospital of Philadelphia, Dr. Hakon Hakonarson, MD, PhD., Director of CAG, Email: hakonarson@chop.edu

Keywords: AI, Cancer Vaccine, deep learning, large language models

Amount: $25000

Intellectual Property Status: None

Award Date: 08/01/2024

End Date: 07/31/2025

ABSTRACT

This project aims to develop a novel personalized cancer vaccine design technology by leveraging deep learning and large language models to integrate multi-omics data, identify patient-specific neoantigens, and generate optimized peptide sequences for improved immunogenicity and manufacturability.