Robert A. Holton, an esteemed organic chemist and professor at Florida State University, passed away at age 81 on May 21, 2025. He was best known for developing a semisynthetic method to produce the cancer drug Taxol (paclitaxel), enabling its large-scale manufacturing and preserving endangered Pacific yew trees. This breakthrough led to lifesaving treatments for breast, lung, and ovarian cancers, among others. Holton’s innovation generated over $350 million in royalties for FSU and helped establish biotech company Taxolog. A fellow of the National Academy of Inventors, he retired in 2023, leaving a legacy of scientific and medical impact. Learn more about Holton and his career at: