STRP

University of Wyoming

Sensitive Lateral Flow Assay using Dissolvable Nasal Swabs

Lead: Debashis Dutta

Keywords: rapid, influenza, diagnostic, sensitive,

Amount: $150000.00

Intellectual Property Status: Invention disclosure

Award Date: 10/01/2024

End Date: 09/30/2026

ABSTRACT

Influenza (flu) infections are commonly diagnosed using Rapid Influenza Diagnostic Tests or RIDTs that are inexpensive, do not require specialized equipment, and can provide results within 15 minutes. RIDTs, however, often produce false negative results requiring that their outcomes be validated with advanced tests which largely compromises their time and cost benefits. In this project, we propose to improve RIDT sensitivity by developing a nano-particle based Lateral Flow Immunoassay (LFIA) device capable of analyzing low-volume nasal swab samples, thereby resulting in higher accuracy.